Platelet-Rich Plasma (PRP) and Growth Factor Concentrate (GFC) are popular autologous treatments for androgenetic alopecia and skin rejuvenation. Both use the patient's own blood to extract regenerative cells.
1. PRP vs. GFC: Understanding the Difference
PRP relies on extracting concentrated platelets, which release growth factors after injection. GFC is a newer development where platelets are pre-activated inside specialized tubes to release growth factors directly into the serum, resulting in a cleaner, acellular preparation with less post-procedure pain.
2. Spin Speeds and Centrifugation
Achieving the correct concentration requires precise centrifugation. A double-spin method (an initial soft spin to separate red blood cells, followed by a hard spin to concentrate platelets) is recommended to ensure high platelet recovery rates.
Frequently Asked Questions
PRP injects platelets that release growth factors in the scalp. GFC pre-activates the platelets inside a tube to extract the pure growth factors, injecting an acellular serum.
The first spin separates plasma and platelets from red blood cells. The second spin concentrates the platelets in a smaller volume, creating true platelet-rich plasma.
Patients usually require 4 to 6 sessions spaced 4 weeks apart. Maintenance treatments are recommended every 6 months to sustain hair density.
Downtime is minimal. The scalp may feel sore or tight for 24 hours. Patients should avoid washing their hair or using chemical treatments for 24 hours.
These therapies stimulate weak hair follicles and increase hair thickness, but they cannot alter genetic hair loss. Ongoing treatments are required to maintain results.
Yes, because GFC is acellular (free of red and white blood cells), it causes significantly less tissue inflammation and injection pain compared to PRP.
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